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Acute pancreatitis: Frequently Asked Questions

Who is affected by acute pancreatitis?

The disease affects men more often than women. It occurs in 4 out of 10,000 people. Alcohol abuse is a common risk factor.

How is acute pancreatitis treated?

Treatment is aimed at resting the pancreas, supporting the patient with IV fluid, and providing pain relief. The pancreas is rested by avoiding food or drink. A nasogastric tube may also be passed into the stomach to remove the contents of the stomach so that they do not pass into the small intestine and stimulate the pancreas. The nasogastric tube may also be placed if there is persistent vomiting, severe pain, or a paralytic

What is the prognosis for acute pancreatitis?

In most cases, the symptoms resolve in approximately week. However, in some cases, life-threatening illness develops. The death rate is high with hemorrhagic pancreatitis when complications such as liver, heart, or kidney impairment are present. Recurrences are common. The more recurrences there are, the more scarred the pancreas becomes, leading to more severe complications.

What is acute pancreatitis?

Acute pancreatitis is an acute inflammation of the pancreas. In 80-85% of the cases, acute pancreatitis is mild and heals fully in a few days. However, a very severe and life-threatening inflammation can develop requiring hospitalization in an intensive care unit and in some cases surgery.
This is an acute inflammation of the pancreas, triggered by gallstones, which block the pancreatic duct, or too much alcohol, which irritates the pancreas until it becomes inflamed. In rare cases, acute pancreatitis can be caused by drugs. Acute pancreatitis is always a dangerous illness and must always be treated in hospital. There is a risk that pancreatic enzymes will cause the body to digest itself (autodigestion)! ...
Acute pancreatitis is a sudden inflammation of the pancreas which is usually associated with severe upper abdominal pain.

How is recurrence of acute pancreatitis prevented?

Recurrence of the attack may be prevented by treating the underlying condition.

What types of complications can occur with acute pancreatitis?

Low blood pressure, organ failure (heart, kidney), respiratory distress syndrome, pancreatic cyst and/or abscess, ascites, chronic

What is the treatment for acute pancreatitis?

Treatment for acute pancreatitis depends on the severity of the condition. Sometimes the patient needs hospitalization with administration of intravenous fluids to help restore blood volume. Antibiotics are often prescribed if infection occurs and pain medications are often used to provide relief. Surgery is sometimes needed when complications such as infection, cysts or bleeding occur).

How is acute pancreatitis diagnosed?

Diagnosing acute pancreatitis is often difficult because of the deep location of the pancreas. A physical exam and blood tests to determine the levels of amylase and lipase are often the first tools used to begin the diagnosis. When radiography is necessary, state-of-the-art techniques and equipment is recommended for accurate diagnosis. ...

What are the causes of acute pancreatitis?

The most common cause is gallstones. Other causes include alcohol abuse, hereditary conditions, trauma, medications, infections, electrolyte abnormalities, high lipid levels and hormonal abnormalities. In approximately 15% of cases, the cause of acute pancreatitis is unknown.

How frequently is there no clear cause for acute pancreatitis?

In approximately 10-20% of cases of acute pancreatitis, there is no readily identifiable cause and it is termed idiopathic.

What are the common causes of acute pancreatitis?

In the United States and in many parts of the world, alcohol and gallstones are the two most common causes of acute pancreatitis. Other causes include drugs, infectious agents, hypertriglyceridemia, trauma, and pancreatic duct obstruction.
The most common causes of acute pancreatitis in adults are gallstones, other diseases related to the gallbladder, and alcohol use.

How is acute pancreatitis normally treated?

Acute pancreatitis should be treated in a hospital. In the early stages, the patient should neither eat nor drink and will receive fluids and nutrition through a vein (intravenously). Additionally, pain killers are prescribed. Depending on the severity further measures such as the use of a catheter in a large vessel as well as in the bladder. For diagnostic purposes an ultrasound or, in certain cases, a computerized tomography (CT) scan of the abdomen may be required. ...

Which medications can cause acute pancreatitis?

Estrogens, corticosteroids, thiazide diuretics, acetaminophen, and tetracycline are some medicines which can cause acute pancreatitis.

How can acute pancreatitis be prevented?

Acute pancreatitis can be prevented by preventing its causative factors. Alcohol intake should be controlled or avoided completely if pancreatitis has already occurred. Any gallbladder disease should be treated. If gallstones are present and cause symptoms, a cholecystectomy (removal of gallbladder) should be done. Abdominal trauma should be avoided if pancreatitis has been previously diagnosed.

What are the clinical signs of acute pancreatitis?

Acute pancreatitis generally starts with a pain in the upper abdomen. The pain can be severe, radiate to the back and may last for several days. Relief of pain by sitting up and bending forward is characteristic of pancreatic pain. The pain is often accompanied by nausea and vomiting. Other symptoms include diarrhea, bloating and fever.

What happens in severe cases of acute pancreatitis?

In severe cases the pancreas may become infected and antibiotics will be necessary.

What types of diseases in children can cause acute pancreatitis?

Pancreatitis can occur in children after abdominal trauma or from diseases such as cystic fibrosis, hemolytic uremic syndrome, Kawasaki disease, mumps, Reye's syndrome, and various viral illnesses.

What must I do if a doctor says I have acute pancreatitis?

As it is difficult to determine in the early stages whether it is a mild or severe form, acute pancreatitis should, when possible, be treated in a hospital. The most common causes of acute pancreatitis are gallstones and heavy alcohol use. If gallstones are diagnosed, the gallbladder including the stones should be removed. When this is done, depends upon the severity of the pancreatitis. If heavy alcohol use is the cause, total alcohol abstinence is strongly recommended.

I have recurrent acute idiopathic pancreatitis. Why should I have my gallbladder removed?

This is because many patients in your condition are eventually found to have microlithiasis (sludge or very small stones). Some patients have genetic mutations in the trypsinogen gene or the cystic fibrosis gene.

On Thursday, July 26th, my father was diagnosed and admitted to the hospital with acute pancreatitis. He died on July 28th, 30 hours after admission. Can one die from acute pancreatitis?

Most attacks of acute pancreatitis are mild. Patients will generally improve after 3-5 days. Ocassionally, however, pancreatitis may become severe and life threatening. In these cases mortality rate can be quite high.
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