Hydrea, Hydroxyurea (generic): Frequently Asked Questions
Can EXJADE be taken with hydroxyurea?
The interaction of EXJADE with hydroxyurea has not been formally studied. No inhibition of deferasirox metabolism by hydroxyurea is expected based on the results of an in vitro study.
Source: www.us.exjade.com
Is Hydrea Safer Than the Older Agents?
Some doctors feel very comfortable with its use, some do not like to use it in younger patients who will require treatment for many years but feel comfortable using it in older patients who are unlikely to remain on it long enough to develop any secondary problems. The literature reports of secondary leukemias associated with prolonged Hydrea therapy indicate the risk is lower than older agents. ...
Source: www.acor.org
WHAT IS HYDROXYUREA?
Hydroxyurea (HydreaŽ) is a drug used for antiviral therapy. It is manufactured by Bristol-Myers Squibb. Hydroxyurea is sometimes referred to as HU. Hydroxyurea was approved for use against cancer. It also works against sickle cell anemia. Hydroxyurea has not yet been approved by the FDA for use against HIV. Hydroxyurea blocks an enzyme produced by human cells. This enzyme makes building blocks used by cells that are multiplying. ...
Source: www.voy.com
HOW IS HYDROXYUREA TAKEN?
Hydroxyurea is available in 500 mg tablets. The most common doses studied have been 1 gram taken once a day, or 500 mg taken twice a day. Scientists are working to find out the best dose of hydroxyurea for people with HIV.
Source: www.voy.com
Is treatment with hydroxyurea safe and effective?
Hydroxyurea has been found to be effective in the majority of sickle cell patients who receive this treatment. Hydroxyurea decreases the frequency of painful episodes, decreases the incidence of acute chest syndrome (a complication of sickle cell disease characterized by changes on chest x–ray, pain, decreased blood counts and sometimes respiratory failure), and reduces or prevents priapism (persistent erection of the penis, accompanied by pain and tenderness). ...
Source: www.ihtc.org
How Long Do I Have to Take Hydrea?
Unless your doctor changes you to another treatment agent, for life. PV is a chronic condition. The rapid rebound following drug withdrawal requires continuous administration.
Source: www.acor.org
Unless your doctor changes you to another treatment agent, for life. Polycythemia vera is a chronic condition. The rapid rebound following drug withdrawal requires continuous administration.
Source: www.mpd-rc.org
How Long Will I Have to Take Hydrea or other drugs?
Because PV is a chronic condition, indefinitely, unless your doctor changes you to another treatment agent. Blood counts generally rebound rapidly once HU is stopped, whereas a period of remission is sometimes experienced after stopping Interferon.
Source: www.mpdinfo.org
WHO SHOULD TAKE HYDROXYUREA?
Hydroxyurea has been studied in combination with the antiviral drugs ddI and d4T. Most doctors start antiviral therapy when a person has some symptoms of HIV disease, when their T-cell count (CD4+ cells) falls below 350, or if their viral load is over 30,000. There are no absolute rules about when to start antiviral drugs. Some people want to "hit HIV hard and early", starting with the strongest drugs to preserve the immune system. ...
Source: www.voy.com
Is Hydrea safer than the other agents?
Some doctors feel very comfortable with its use, some do not like to use it in younger patients who will require treatment for many years but feel comfortable using it in older patients who are unlikely to remain on it long enough to develop any secondary problems. The literature suggests that the risk of secondary leukemias is lower with prolonged Hydrea therapy in comparison to older agents.
Source: www.mpd-rc.org
WHAT IS HYDREA AND WHAT SIDE EFFECTS CAN I EXPECT?
Hydrea is the commonly used name for hydroxyurea, an antimetabolite used to treat CML. Taken by mouth, it alters blood chemistry to reduce the number of white blood cells to a normal range. Like any other medicine, it has side effects. GI upset is not uncommon It is important to be monitored by your doctor while taking hydrea. Your immune system may be more fragile, and it is wise to avoid people with contagious illnesses or getting minor injuries. ...
Source: www.mpdinfo.org
Will I Still Need Phlebotomies If I am taking Hydrea?
Because hydroxyurea has less of a suppressive effect on erythropoiesis (red cell production ) than on platelet and neutrophil production, supplementary phlebotomies may be required for the maintenance of an optimal hematocrit. [Return to the index]
Source: www.acor.org
Because hydroxyurea has less of a suppressive effect on erythropoiesis (red cell production ) than on platelet and neutrophil (a type of white blood cell) production, supplementary phlebotomies may be required for the maintenance of an optimal hematocrit, but this varies considerably between individuals.
Source: www.mpdinfo.org
Because hydroxyurea has less of a suppressive effect on erythropoiesis (red cell production ) than on platelet and neutrophil production, supplementary phlebotomies may be required for the maintenance of an optimal hematocrit.
Source: www.mpd-rc.org
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